, 3-Methyl-1-phenyl-2-pyrazolin-5-one(Edaravone) ,

：纯度：>95% (HPLC) CAS：

英文名称：3-Methyl-1-phenyl-2-pyrazolin-5-one(Edaravone)

品牌：TRC

规格	目录价格	上海	会员价格	数量
1g	￥ ǶƄƄƓƭǠȰ	0	一般3-5周，以TRC实际库存为准	￥ ǶƄƄƓƭǠȰ	- +

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检测信息

COA 12-FGD-804-1

基本信息

英文名称

3-Methyl-1-phenyl-2-pyrazolin-5-one(Edaravone)

分子式

C10 H10 N2 O

Smiles Code

纯度

>95% (HPLC)

Standards; Pharmaceutical/API Drug Impurities/Metabolites;

Edaravone inhibits the disease activity in rheumatoid arthritis. Edaravone can significantly enhance IR flap viability and protect flap vessels, which is related to scavenging oxygen free radicals, reducing the consumption of SOD, reducing the extent of lipid peroxidation and inflammation, and protecting functional structure of vessels in the early stages of reperfusion. It also shows protective effects against STZ-induced cognitive impairment, oxidative stress, cholinergic dysfunction and altered protein expressions. Its acts like a free radical scavenger, decreased apoptotic cell death, oxidative damage to DNA and lipids, and angiogenesis through inhibiting JNK and p38 MAPK pathways in AMD, glaucoma, DR, and RVO animal models.

Reeta KH et al. Eur J Neurosci. 2017 Feb 15Masuda T et al. Oxid Med Cell Longev. 2017;2017:9208489Zhang DY et al. J Huazhong Univ Sci Technolog Med Sci. 2017 Feb;37(1):51-56Criswell LA et al. Am J Med. 2002 Apr 15;112(6):465-71.

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摩尔计算器

质量 (g) = 浓度 (mol/L) × 体积 (L) × (g/mol)

质量			浓度			体积			*
		=			×			×

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