| Norverapamil (hydrochloride) | - 亚薄世界杯试剂

：纯度：98% CAS：

英文名称：Norverapamil (hydrochloride)

规格	目录价格	安徽	武汉	成都	北方	深圳	会员价格	数量
2mg	￥ ƁǤƉŶƉƉ	--	--	--	--	--	--	￥ ƁǤƉŶƉƉ	- +
5mg	￥ ǼǤǤƉŶƉƉ	--	--	--	--	--	--	￥ ǼǤǤƉŶƉƉ	- +
0mg	￥ ŞǤǤƉŶƉƉ	--	--	--	--	--	--	￥ ŞǤǤƉŶƉƉ	- +
25mg	￥ ǤǼƉƉŶƉƉ	--	--	--	--	--	--	￥ ǤǼƉƉŶƉƉ	- +

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检测信息

Data Sheet

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产品名称：(R)-Verapamil (hydrochloride) 纯度：98%

：8230

CAS号：387-02-2

￥ ŞƉƉƉŶƉƉ /5mg

￥ ƿƷƉƉŶƉƉ /0mg

￥ ǼǼƉƉƉŶƉƉ /50mg

￥ ǼĝǤƉƉŶƉƉ /00mg

现货

基本信息
属性
计算化学
参考文献
安全信息

英文名称

Norverapamil (hydrochloride)

英文别称

(±)-Norverapamil (hydrochloride); D59 (hydrochloride)

中文别称

Smiles Code

N#CC(C(C)C)(CCCNCCC=CC=C(OC)C(OC)=C)C2=CC=C(OC)C(OC)=C2.[H]Cl

分子式

C2H37ClN2O4

纯度

98%

诺维拉帕米是维拉帕米的 N-去甲基化代谢物。它具有显着较低的钙通道阻断能力并表现出治疗活性。

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72.74

[]. Adams KN, et al. Verapamil, and its metabolite norverapamil, inhibit macrophage-induced, bacterial efflux pump-mediated tolerance to multiple anti-tubercular drugs. J Infect Dis. 204 Aug ;20(3):45-.

[2]. Choi DH, et al. Effects of simvastatin on the pharmacokinetics of verapamil and its main metabolite, norverapamil, in rats. Eur J Drug Metab Pharmacokinet. 2009 Jul-Sep;34(3-4):3-8.

[3]. Pauli-Magnus C, et al. Characterization of the major metabolites of verapamil as substrates and inhibitors of P-glycoprotein. J Pharmacol Exp Ther. 2000 May;293(2):37-82.

[4]. Wang J et al. A semi-physiologically-based pharmacokinetic model characterizing mechanism-based auto-inhibition to predict stereoselective pharmacokinetics of verapamil and its metabolite norverapamil in human. Eur J Pharm Sci. 203 Nov 20;50(3-4):290-302.

[5]. Amy C Young, et al. Intravenous fat emulsion therapy for intentional sustained-release verapamil overdose. Resuscitation. 2009 May;80(5):59-3.