9.5
[1]. Yangbing Li, et al. Discovery of MD- as a First-in-Class, Highly Potent, and Efficacious Proteolysis Targeting Chimera Murine Double Minute Degrader Capable of Achieving Complete and Durable Tumor Regression. J Med Chem. 019 Jan ;():8-.
[]. Zhou B, et al. Discovery of a Small-Molecule Degrader of Bromodomain and Extra-Terminal (BET) Proteins with Picomolar Cellular Potencies and Capable of Achieving Tumor Regression. J Med Chem. 018 Jan 5;1():-81.
H30-H315-H319-H335
P1-P-P70-P71-P80-P30+P35-P30+P30-P305+P351+P338-P330-P3+P3-P03+P33-P05-P501